The Doctor's Farmacy With Mark Hyman, M.d.

What if we could predict disease before it even starts? In this episode, I’m joined by Dr. Jeremy Nicholson to explore the cutting-edge science of precision medicine and how understanding your unique biology could hold the key to preventing illness. We dive into the future of diagnostics, the power of the exposome in shaping your health, and how advancements like gene editing could revolutionize treatment.  In this episode, we discuss: The emerging field of phenomic medicine Moving away from one-size-fits-all treatments toward more personalized medical approaches based on individual biology Long COVID and its impact The critical role of the microbiome in overall health, immune system function, and its direct influence on diseases How the exposome, or all of the environmental exposures a person experiences, plays a crucial role in shaping health outcomes Advanced technologies like metabolic profiling, which can reveal subtle biochemical signals and identify disease risks long before symptoms appear. How

Have you ever wondered why it’s so hard to put down that bag of chips? In this episode, my guests Dr. Shebani Sethi and Calley Means and I break down how ultra-processed foods are contributing to the obesity epidemic, diabetes, heart disease, and even mental health issues. From understanding the science of addiction to decoding food labels, we’ll explore how big food companies are manipulating us—and what we can do to fight back. View Show Notes From This Episode Get Free Weekly Health Tips from Dr. Hyman Sign Up for Dr. Hyman’s Weekly Longevity Journal Full-length episodes of these interviews can be found here: Why the Last Thing that Should Ever Eat is Ultra Processed Foods: It Kills 11 Million People a Year How Does Ultra-Processed Food Affect Our Mental Health? Calley Means: The Obesity Crisis, Ozempic, ADHD and Food Industry Lies This episode is brought to you by Rupa Health, FOND, Ketone-IQ, and Happy Egg. Streamline your lab orders with Rupa Health. Access more than 3,500 specialty lab tests and regist

Most people have no idea they’re missing out on essential nutrients—until it’s too late. In this episode, I expose the hidden truth behind nutrient deficiencies and why supplements are no longer optional when it comes to your health. Learn which supplements are vital to keep you feeling your best and how to navigate the confusing supplement market with confidence. View Show Notes From This Episode Get Free Weekly Health Tips from Dr. Hyman Sign Up for Dr. Hyman’s Weekly Longevity Journal This episode is brought to you by AG1, Seed, and Essentia. Get your daily serving of vitamins, minerals, adaptogens, and more with AG1. Head to DrinkAG1.com/Hyman and get a year's worth of D3 and five Travel Packs for FREE with your first order. Seed is offering my community 25% off to try DS-01® for themselves. Visit seed.com/hyman and use code HYMAN25 for 25% off your first month of Seed's DS-01® Daily Synbiotic. Get an EXTRA $100 off your mattress purchase, on top of Essentia’s Labor Day Sale of 25% OFF + FREE organic cott

Fatty liver disease is on the rise, but the good news is, it’s preventable and reversible. In this episode, I sit down with Dr. Yousef Elyaman to explore the silent epidemic and how early detection could be the key to saving your liver—and your health. We break down the latest in diagnostic tools and dive into powerful lifestyle interventions. Whether you’ve been diagnosed or want to stay ahead of the game, this episode is packed with practical advice to protect your liver and your health. In this episode, we discuss: The importance of diagnosing fatty liver disease early through blood tests How dietary interventions, particularly the Mediterranean diet, can significantly improve or even reverse fatty liver disease Supplements that support liver function and reverse fatty liver disease How insulin resistance is a major contributor to fatty liver disease and why managing blood sugar levels is critical for liver health The connection between chronic inflammation and fatty liver disease How exposure to tox

Struggling with skin issues like acne or rosacea? In this episode, I team up with Dr. Todd LePine and Dr. Elizabeth Boham to dive deep into the root causes behind chronic skin conditions. We break down how gut health, food sensitivities, and systemic inflammation are often at the heart of these issues. Learn how eliminating processed foods, gluten, and dairy can transform your skin, and why treating from the inside out is the key to lasting skin health. View Show Notes From This Episode Get Free Weekly Health Tips from Dr. Hyman Sign Up for Dr. Hyman’s Weekly Longevity Journal Full-length episodes of these interviews can be found here: Treating Adult Acne & Rosacea From The Inside Out How To Heal Skin Issues By Optimizing Your Nutrient Status And Fixing Your Gut Treating Acne From The Inside Out with Dr. Elizabeth Boham This episode is brought to you by Eudemonia, ButcherBox, and Cozy Earth. For the full lineup and to purchase a ticket, visit Eudemonia.net. ButcherBox is giving new members two pounds of wild-

Think weight training is just for bodybuilders? In this episode, I break down why building muscle is one of the most important things you can do for your long-term health. From improving insulin resistance and boosting your metabolism to enhancing mental clarity and protecting against chronic diseases like diabetes, heart disease, and Alzheimer's—muscle is the secret weapon you didn’t know you needed. I’ll also share practical tips for incorporating strength training into your routine, no matter your age or fitness level. View Show Notes From This Episode Get Free Weekly Health Tips from Dr. Hyman Sign Up for Dr. Hyman’s Weekly Longevity Journal This episode is brought to you by Mitopure, OneSkin, Seed, and AX3. Support essential mitochondrial health and save 10% on Mitopure. Visit TimelineNutrition.com/Drhyman and use code DRHYMAN10. Unlock your healthiest skin yet. Try OneSkin with 15% off your first purchase using code HYMAN15 at OneSkin.co today. Seed is offering my community 25% off to try DS-01® for the

Have you ever experienced unexplained allergy-like symptoms, digestive issues, or persistent fatigue? It could be histamine intolerance, a condition that’s more common than you think. In this episode, Dr. Elizabeth Boham joins me to examine real patient stories, dive deep into the gut-brain connection, and share how you can manage histamine intolerance through personalized treatments, stress management, and gut health optimization. Whether it's genetic or lifestyle-related, histamine intolerance doesn't have to be a lifelong battle.  In this episode, we discuss: The common symptoms of histamine intolerance The importance of the DAO enzyme Why low-histamine diets may not be a long-term solution Why stress and gut health are key triggers The difference between histamine intolerance and and mast cell activation syndrome (MCAS) View Show Notes From This Episode Get Free Weekly Health Tips from Dr. Hyman Sign Up for Dr. Hyman’s Weekly Longevity Journal This episode is brought to you by Rupa Health, Pendulum,

Is going gluten-free just a trend, or is it a legitimate step toward better health? In this episode, I’m joined by Dr. Alessio Fasano and Maggie Ward to explore the science behind gluten sensitivity and why modern bread could be at the root of many gut issues. We dive into the debate over gluten-free diets, discussing whether they’re necessary for everyone or only for those with celiac disease. We also examine how environmental factors like pesticides and hybridized wheat are disrupting the gut microbiome, leading to issues like leaky gut syndrome. View Show Notes From This Episode Get Free Weekly Health Tips from Dr. Hyman Sign Up for Dr. Hyman’s Weekly Longevity Journal Full-length episodes of these interviews can be found here: Is Gluten-Free A Fad Or Is Gluten A Real Threat To Our Health? Should We All Avoid Gluten? What Would Happen If You Stopped Eating Bread For 30 Days? This episode is brought to you by Momentous, AG1, and Happy Egg. Head over to LiveMomentous.com/Mark for 20% off creatine, collagen,

Tired of dealing with constant bloating and discomfort? In this episode, I break down the root causes of IBS and other common gut problems, from food sensitivities and SIBO to the gut-brain connection and stress. We’ll explore why ultra-processed foods are wreaking havoc on your gut, and I’ll walk you through the 5 R program and strategies like the low FODMAP diet to heal your gut for good. If you're suffering from bloating, constipation, or gas, this episode is your guide to real relief. View Show Notes From This Episode Get Free Weekly Health Tips from Dr. Hyman Sign Up for Dr. Hyman’s Weekly Longevity Journal This episode is brought to you by AG1 and Rupa University. Get your daily serving of vitamins, minerals, adaptogens, and more with AG1. Head to DrinkAG1.com/Hyman and get a year's worth of D3 and five Travel Packs for FREE with your first order. Rupa University is hosting FREE classes and bootcamps for healthcare providers who want to learn more about Functional Medicine testing. Sign up at RupaUniver

Muscle isn’t just about strength—it’s about longevity, metabolic health, and even immune function. In this episode, I sit down with Dr. Gabrielle Lyon to uncover the critical role that skeletal muscle plays in our overall health. We dive deep into muscle as an endocrine organ, its role in fighting insulin resistance, and why sedentary lifestyles are wreaking havoc on our bodies. From understanding how to build muscle effectively at any age to learning why muscle mass is the key to metabolic health, this conversation will change the way you think about strength training. In this episode, we discuss: Exactly how much protein we need to eat every day The differences between plant and animal proteins The impact of resistance training The metabolic benefits of muscle Why you should spread your protein intake evenly throughout the day How sedentary behavior and insufficient protein intake can lead to muscle loss, insulin resistance, and metabolic disorders View Show Notes From This Episode Get Free Weekly He

Are you getting enough vitamin D? This powerful nutrient does so much more than just support bone health—it’s essential for mood, energy, immunity, and even protection against serious diseases like cancer and COVID. Yet, approximately 80% of Americans are deficient due to limited sun exposure and the depletion of nutrients in our modern food supply. In this episode, I break down why vitamin D is critical for your health, the optimal levels you should aim for, and how to get your daily dose safely—whether through the sun, diet, or supplements. View Show Notes From This Episode Get Free Weekly Health Tips from Dr. Hyman Sign Up for Dr. Hyman’s Weekly Longevity Journal Full-length episodes of these interviews can be found here: Do You Need To Take Vitamin D? Supplements: Useful Or Useless? with Dr. Elizabeth Boham The Science Behind Vitamin D, Our Rampant Deficiency, And Its Harmful Impact On Our Health This episode is brought to you by Pique, Eudemonia, Ketone-IQ, and Happy Egg. Head over to PiqueLife.com/Hyman

We often think of trauma as those big, life-shattering events, but did you know that everyday stress can have the same lasting impact on your health? In this episode, I break down how both major and minor traumas affect your body at the deepest level—from your gut to your brain—and what you can do to heal. We’ll dive into the science of how trauma shapes your biology and explore the functional medicine strategies that go beyond traditional talk therapy. Whether you’ve been through a major event or are feeling the weight of everyday stress, this episode offers powerful tools to help you not just survive, but thrive. View Show Notes From This Episode Get Free Weekly Health Tips from Dr. Hyman Sign Up for Dr. Hyman’s Weekly Longevity Journal This episode is brought to you by Cozy Earth, AG1, AX3. Right now, you can save 40% when you upgrade to Cozy Earth sheets. Just head over to CozyEarth.com. Get your daily serving of vitamins, minerals, adaptogens, and more with AG1. Head to DrinkAG1.com/Hyman and get a year'

What if the key to fixing our broken healthcare system lies within Congress? On this episode of “The Doctor’s Farmacy,” I sit down with U.S. Representative Vern Buchanan to tackle one of the biggest crises facing our country: the rise of chronic disease and its staggering economic impact. We dive deep into why prevention, not just treatment, needs to be at the forefront of healthcare, and discuss the groundbreaking work being done in Congress to shift our focus toward nutrition, lifestyle changes, and medically tailored meals.  In this episode, we discuss: The staggering economic burden of chronic diseases on the U.S. economy The importance of nutrition education for doctors and healthcare providers as a key factor in preventing chronic diseases Congressman Vern Buchanan’s bipartisan efforts to address the chronic disease epidemic through policy changes and initiatives like the Congressional Preventive Health and Wellness Caucus The impact of chronic disease on military readiness and national security Th

Did you know chronic stress can age your immune system faster than almost anything else? In this episode, I dive into the fascinating world of immune and lymph health with some of the leading experts in the field, including Dr. Mehmet Oz, Dr. Gerald Lemole, and Dr. Leonard Calabrese. We explore how stress, diet, and lifestyle can either rejuvenate or break down your immune defenses, leading to a host of chronic conditions. Learn practical, science-backed strategies to boost your immune resilience, reduce inflammation, and keep your body’s defenses in top shape. View Show Notes From This Episode Get Free Weekly Health Tips from Dr. Hyman Sign Up for Dr. Hyman’s Weekly Longevity Journal Full-length episodes of these interviews can be found here: How To Reset Your Immune System At A Cellular Level Why Our Neglected Lymph System Is A Key To Optimal Health The Secrets to Creating a Healthy Immune System This episode is brought to you by Mitopure, Eudemonia, SleepMe, and Sunlighten. Support essential mitochondrial

Could your persistent acne, eczema, or psoriasis be a sign of something more serious? Join me on "The Doctor’s Farmacy" as I reveal how chronic skin conditions are often linked to gut health and nutrient deficiencies. I’ll share practical tips on how to support your skin by healing your gut, optimizing your diet, and identifying the root causes of inflammation. It’s time to understand what your skin is really telling you and how to fix it. View Show Notes From This Episode Get Free Weekly Health Tips from Dr. Hyman Sign Up for Dr. Hyman’s Weekly Longevity Journal This episode is brought to you by AG1 and Essentia. Get your daily serving of vitamins, minerals, adaptogens, and more with AG1. Head to DrinkAG1.com/Hyman and get a year's worth of D3 and five Travel Packs for FREE with your first order. Enjoy an extra $100 off your organic mattress purchase with code HYMAN at checkout on Essentia's site. Visit MyEssentia.com/DrMarkHyman for more details. Learn more about your ad choices. Visit megaphone.fm/adchoice

Do you ever feel like the more meds you take, the worse you feel? The problem might lie in how our healthcare system operates. In this episode, I sit down with Dr. Marty Makary to tackle the alarming rise of colon cancer among young people, explore how our microbiome plays a crucial role in preventing chronic diseases, and discuss the unsettling influence of the pharmaceutical industry on medical practices. From the impact of antibiotics on children to the hidden dangers of over-medication, we unpack the urgent need for more transparency and a shift towards addressing the root causes of illness. In this episode, we discuss: The alarming increase in colon cancer among young people The microbiome's impact on overall health, from regulating the immune system to influencing mood and metabolism The deep influence of pharmaceutical companies on medical research, education, and policy, often at the expense of patient care The long-term health consequences of early antibiotic use in children The overmedication o

Did you know that sugar is lurking in more places than you might think, and it could be sabotaging your health in ways you never imagined? In this episode, I look back on my conversations with Dr. Richard Johnson and Dr. Robert Lustig. We examine how certain foods, especially those loaded with sugar, can trigger overeating, disrupt your metabolism, and lead to a cascade of health issues. Plus, I'll share practical strategies for detoxing from sugar, managing blood sugar levels, and reclaiming your health. View Show Notes From This Episode Get Free Weekly Health Tips from Dr. Hyman Sign Up for Dr. Hyman’s Weekly Longevity Journal Full-length episodes of these interviews can be found here: Why Sugar And Fructose Are So Deadly with Dr. Richard Johnson Depressed or Anxious? You May Never Eat Sugar Again After Watching This The True Dangers Of Sugar with Dr. Robert Lustig This episode is brought to you by FOND, Mitopure, and Happy Egg. Get 20% off one-time orders for both new and returning customers. Just visit Fo

Are you tired of feeling tired all the time? You're not alone—burnout is one of the most common complaints I hear from patients. In this episode, I dive into the root causes of chronic fatigue, including how mitochondrial dysfunction could be sabotaging your energy levels. I’ll share my personal journey with chronic fatigue and explain how functional medicine can help you boost your energy and finally feel like yourself again. View Show Notes From This Episode Get Free Weekly Health Tips from Dr. Hyman Sign Up for Dr. Hyman’s Weekly Longevity Journal This episode is brought to you by AG1 and Rupa Health. Get your daily serving of vitamins, minerals, adaptogens, and more with AG1. Head to DrinkAG1.com/Hyman and get a year's worth of D3 and five Travel Packs for FREE with your first order. Streamline your lab orders with Rupa Health. Access more than 3,500 specialty lab tests and register for a FREE live demo at RupaHealth.com. Learn more about your ad choices. Visit megaphone.fm/adchoices

In a world where chronic illness and unexplained health issues are on the rise, understanding the root causes behind immune dysfunction is more important than ever. In this episode of "The Doctor's Farmacy," I'm joined by Dr. Elroy Vojdani to explore the critical issue of immune resilience and its connection to chronic illness. Dr. Vojdani shares groundbreaking insights from his father’s work on immune health, along with practical strategies to boost your immune system, tackle long COVID, and reverse chronic conditions through personalized, functional medicine approaches. In this episode, we discuss: The Decline of Immune Resilience The Role of the Gut in Immune Health The Impact of Long COVID on the Immune System Molecular Mimicry and Autoimmunity The Connection Between Mitochondrial Dysfunction and Chronic Illness View Show Notes From This Episode Get Free Weekly Health Tips from Dr. Hyman Sign Up for Dr. Hyman’s Weekly Longevity Journal This episode is brought to you by Rupa Health, Pendulum, Neuroha

Ever wondered why you’re always tired, achy, or just not feeling your best? It could be chronic inflammation silently wreaking havoc on your health—but the good news is, there’s a way to stop it. Joined by experts Dr. Shilpa Ravella and Dr. David Furman, we explore the surprising ways your diet, environment, and even your daily habits might be fueling this silent killer. We break down the science behind inflammation, how it’s linked to almost every chronic disease, and what you can do to stop it in its tracks. View Show Notes From This Episode Get Free Weekly Health Tips from Dr. Hyman Sign Up for Dr. Hyman’s Weekly Longevity Journal Full-length episodes of these interviews can be found here: What Causes Inflammation And How Can You Treat It? The Silent Killer: Inflammation And Chronic Disease How Silent Inflammation Accelerates Aging This episode is brought to you by Momentous, ButcherBox, and SleepMe. Head over to LiveMomentous.com/Mark for 20% off creatine, collagen, and all of their best-in-class products