Start The Week

Women are faring better than men in the coronavirus pandemic because of their genetic superiority, according to the physician Sharon Moalem. He tells Kirsty Wark that women live longer than men and have stronger immune systems because they have two x chromosomes to choose from. In his book, The Better Half, Moalem calls for better understanding of the genetic gender gap and for a change to the male-centric, one-size-fits-all view of medical studies.But if women have greater advantage genetically, where did the prevailing idea of fragile female biology come from? In The Gendered Brain the cognitive neuroscientist Gina Rippon traces the ideas of women’s physical inferiority to the 18th century, and later to the brain science of the 19th century. Even after the development of new brain-imaging technologies showed how similar brains are, the idea of the ‘male’ and ‘female’ brain has remained remarkably persistent.Producer: Katy Hickman

Nick Timothy was once described as the ‘toxic’ power behind Theresa May’s early leadership. He talks to Amol Rajan about his experience in frontline government. In his new book, Remaking One Nation, he calls for the rebuilding of a more inclusive conservatism and the rejection of both extreme economic and cultural liberalism. As the Covid-19 pandemic forces the government to take more extreme measures, Timothy argues for a new social contract between the state, big companies and local communities. In recent decades politicians have had to deal with what appears to be an extreme pace of change – in new technology, global markets and increased automation. The Great Acceleration, as it’s been called, has left many communities feeling left behind. But in his forthcoming book, Slowdown, Professor Danny Dorling argues that there's actually been a widespread check on growth and speed of change. He sees this as a moment of promise and a move toward stability. But that stability may be short-lived as the fall out

We think of our era as the age of celebrity. Billions of people follow the daily antics of the Kardashian family or the latest pop superstar. But celebrity obsession is centuries old, argues Horrible Histories writer Greg Jenner. He tells Tom Sutcliffe why we are captivated by famous - and infamous - figures, from the scandalous Lord Byron to the unwitting civilians who are hounded by paparazzi today. The Italian Renaissance gave us the world's most famous images: the Mona Lisa, Botticelli's Venus and Michelangelo's David. But Catherine Fletcher argues that this era was far stranger, darker and more violent than we may realise. The real Mona Lisa was married to a slave-trader, and Leonardo da Vinci was revered for his weapon designs. The artist Aubrey Beardsley shocked and delighted Victorian London with his drawings. A new exhibition at the Tate Britain, curated by Caroline Corbeau-Parsons, shows the range of Beardsley's black-and-white images. Some are magical, humorous, some sexual and grotesque; and toget

Shakespeare has always been central to the American experience, argues the leading scholar James Shapiro. He tells Tom Sutcliffe how Shakespeare has been invoked – and at times weaponised – at pivotal moments in the history of America, from Revolutionary times to today’s divisionary politics.The film critic Mark Kermode celebrates another global phenomenon: cinematic superheroes. The genre stretches back more than eight decades and taps deeply into timeless themes and storytelling traditions. Kermode also shows how spy-heroes such as Bond have shaped our political identity.For the poet Don Paterson, the classic television series The Twilight Zone was the starting point for his latest collection. Elements of horror, science fiction and fantasy provide a backdrop to his exploration of the mid-life crisis.The political theorist Teresa Bejan returns to the world of Shakespeare to explore what appears to be the most modern of dilemmas: Twitter spats and put-downs. Seventeenth-century thinkers understood there were

Morality has been outsourced to the markets and the state, argues the former Chief Rabbi, Jonathan Sacks. He tells Andrew Marr that society has become deeply divided, and that today’s challenges will never be met until we remember the importance of personal morality and responsibility. But this does not mean self-care, self-love and selfies - instead Sacks says we should focus on communities and caring for others.For a decade Mervyn King was the most influential banker in Britain as Head of the Bank of England. In 2008 he oversaw the worst financial and economic crisis since the Great Depression. In his new book, King looks back at his career, exploring the difference between risk and uncertainty. He suggests ways to make decisions for an unknowable future. If you wanted a decision from David Cameron during his time as Prime Minister you would have had to go through ‘the gatekeeper’, Kate Fall. In her memoir of her time at the centre of political power, Fall recalls the highs and lows of working at No. 10, a

Hilary Mantel is the two-time winner of the Man Booker prize. In a special edition of Start the Week with Andrew Marr, she discusses the final book in her Cromwell trilogy. The Mirror and The Light shows 16th-century England beset by rebellion at home, traitors abroad and Henry VIII still desperate for a male heir. In the centre sits Thomas Cromwell, a man who came from nowhere and has climbed to the very heights of power. His vision is an England of the future, but it is the past and the present mood of the King that will prove his downfall.Reader: Ben Miles Photograph: Jeff Overs Producer: Katy Hickman

Leila Slimani is the first Moroccan woman to win France’s most prestigious literary prize, the Prix Goncourt. From stories of poverty, exploitation and sexual addiction she now turns her attention to sexual politics within a deeply conservative culture. She tells Amol Rajan why she wanted to give voice to young Moroccan women suffocating under the strictures of a society which allowed them only two roles: virgin or wife.The writer Olivia Fane questions whether liberal society is really that liberating. In ‘Why Sex Doesn’t Matter’ she argues that women have been sold the idea of sexual freedom, but that this has curtailed the way people think about love and desire.The journalist Sally Howard asks why, after forty years of feminism, women still do the majority of the housework. While straight British women are found to put in 12 more days of household chores than their male partners, in the US young men are now twice as likely as their fathers to think a woman’s place is in the home.But it’s not just women who

Dan Jackson celebrates the distinctiveness of north-east England. He tells Andrew Marr how centuries of border warfare and dangerous industry has forged a unique people in Northumberland. With recent changes in political allegiance in towns and countryside across the region, Jackson questions whether the area can reassert itself after decades of industrial decline, indifference from the south, and resurgence north of the border.The economist Colin Mayer is looking at how to harness the power of patriotism and regional pride to revitalise areas like the North East. He sees a much greater role for the private sector in fostering community cohesion.But patriotism can be a dangerous force in disputed and diverse areas. Kapka Kassabova travels to two of the world’s most ancient lakes set in the borderlands of North Macedonia, Albania and Greece. This ancient meeting place in the southern Balkans has its own unique history of people living in harmony, and then erupting into catastrophic violence. We live in a world

As the 75th anniversary of the Allied bombing of Dresden approaches, the historian Sinclair McKay looks back at the obliteration of a city and its aftermath. He tells Tom Sutcliffe about the terrible suffering of the 25,000 people who were killed in one night. The artist Edmund de Waal is showcasing his latest work in Dresden. The installation ‘library of exile’ is a place of contemplation and dialogue, and celebrates the cultures of migration. De Waal also outlines the importance of Dresden as the centre of European porcelain. In recent decades this former East German city has seen a huge increase in support for far-right groups. The journalist Stefanie Bolzen argues that there are many who feel their lives have not benefited either from the rebuilding of the city after the war or from the unification of Germany since. Sasha Havlicek is the founding CEO of the global counter-extremism organisation, ISD, which studies the online tactics of far-right groups across Europe and the US. She has seen a rise in the

This year is Beethoven's 250th anniversary, and Sir Antonio Pappano is marking the occasion with a new production of Beethoven's only opera, Fidelio. He tells Andrew Marr how this work combined the composer's keen interest in politics with his bold new symphonic style. But Beethoven was never happy with the finished opera, and redrafted it many times. Pappano also tells Andrew about the enormous - and inescapable - influence Beethoven had on later generations.Rembrandt was another artist who had an enormous influence on later generations. But a new exhibition at the Ashmolean in Oxford, curated by An Van Camp, shows the Dutch artist also redrafting and learning his craft. Young Rembrandt assembles drawings and paintings showing Rembrandt's astonishing rise, from unknown teenager to celebrity artist within a decade.Dame Mary Beard looks at a more pervasive artistic influence in her new BBC Two series, The Shock of the Nude. Beard shows how artists from the classical era to the present day have decided what we

The artist Grayson Perry turns to his formative years in a new exhibition of early works, The Pre-Therapy Years. He tells Amol Rajan about the ideas and influences that helped lay the foundations for his work, and about the emergence of his own identity as ‘the Transvestite Potter’. Hashi Mohamed has a very different story of success: he is now a barrister but arrived in Britain aged nine as a child refugee from Somalia. He warns that his own path is denied to the majority of people in Britain. Social mobility is a myth, he says, with power and privilege concentrated among the privately educated population. At just 26 Theresa Lola is already a prize-winning poet and Young People’s Laureate for London. Her first collection, In Search of Equilibrium, is an unflinching study of death and grieving. But she finds hope and solace in words, and believes in the power of poetry to bring about change.Photograph: Grayson Perry as Claire (detail), 1988 © Matthew R Lewis Producer: Katy Hickman

Oliver Cromwell’s Protectorate in the mid-seventeenth century lasted a mere six years and was England’s sole experiment in republican government. The historian Paul Lay tells Andrew Marr how Cromwell forged both his foreign and domestic policy according to God’s will - including waging wars in the Americas.Protestant separatists are at the heart of Stephen Tomkins's recreation of the journey of the Mayflower, three decades before Cromwell’s rule. Escaping religious persecution, the Pilgrim Fathers built their version of a brave new world in America.In the 400 years since the sailing of the Mayflower the USA has become a world superpower. Lindsay Newman from Chatham House looks at President Trump’s foreign policy decisions, especially in relation to Iran, and examines the political ideology that drives them.It is 70 years since the death of George Orwell. The academic Lisa Mullen explores the contemporary relevance of his writings on political and religious ideology, republicanism and the freedom to express he

The economist Daniel Susskind tells Tom Sutcliffe that the threat of technological unemployment is real and imminent. In A World Without Work he considers the economic, political and social impact. He questions what happens to those for whom work affords meaning, purpose and direction. Journalist Anoosh Chakelian went behind the scenes at new magazines set up to rival the Big Issue, as she explored Britain's homelessness crisis. Like the Big Issue, these new journals enable rough sleepers to earn money rather than beg, and creates respectable employment opportunities. But Chakelian worries about a country with so many homeless people that it can create an industry around them.The psychologist Suzi Gage looks at the science behind recreational drugs – debunking common myths and misconceptions. She also looks at how and why they work on the mind and body, and the associations between drug use and mental health.A quarter of adults in England are taking potentially addictive prescription medicines, with half of t

Andrew Marr discusses the state of housing in Britain and what makes a house a home. Common wisdom states that owning a house makes you a Tory, but is this true? Political scientist Ben Ansell says that Thatcher was right to assume that Right to Buy would create more Conservative voters. But today we see the opposite: the people whose houses have risen most in value are also the most likely to support Labour. Ansell looks back at the 1909 British Liberal Party budget, when politicians tried to take on the landlords who get rich at our expense.The architect David Mikhail helped design a groundbreaking council house estate which won last year’s Stirling Prize, awarded to the best new building in the country. As the shortfall in social housing reaches crisis levels, his Goldsmith Street in Norwich was celebrated for creating sustainable and ambitious homes for people in need.The writer Jude Yawson looks back at the emergence of Grime, a music culture which emerged from the tower blocks of East London. The artist

Westminster Abbey has been a place of worship for more than a thousand years, and holds a unique place in British – and world – history. In a special edition of Start the Week, recorded in the Abbey, the historian David Cannadine tells Andrew Marr how the building has been at the centre of religious and political revolutions and has maintained a special relationship with the monarchy and the royal court since the Tudor times.It was Henry VIII who converted the abbey into a cathedral, turning this Catholic monastery into a bastion of Anglicanism, before it became directly under the monarch’s control. The historian Lucy Worsley looks back to the 16th century to recreate how Christmas was celebrated during the age of Henry VIII. The Tudor Christmas pre-dates our traditional trees and stockings. But with its heady mix of revelry and religion she discovers the Tudor influences on the customs we still enjoy today.The former Bishop of Oxford Richard Harries explores the impact and pull of religion on some of the gre

The mathematician Hannah Fry reveals the hidden numbers, rules and patterns that secretly control our daily lives, in this year’s Royal Institution Christmas lectures. She tells Kirsty Wark how maths and algorithms have the power to reveal the truth - and to obscure it.The economist Tim Harford is in search of the truth as he unravels the events that led to real life disasters. In the podcast series Cautionary Tales, Harford asks what we can learn from catastrophes. He wonders why we are so often susceptible to cons. Science has revolutionised the way we live, and in the field of technology the ingenious invention of blockchain has been heralded as truly radical. As an incorruptible digital ledger of transactions, blockchain has uses far beyond crypto-currencies. The Financial Times journalist Izabella Kaminska looks back over the last decade to consider whether blockchain has lived up to its hype.The latest science promising to transform medicine and biology is nanotechnology. Sonia Contera is a pioneer in

Flooding remains a risk in many parts of the country this winter. Andrew Marr explores the impact of water on communities. The engineer David Lerner argues for the extension of the policy of daylighting – opening up rivers covered over by the Victorians. He says Britain’s towns and cities have a lot to learn from Zurich, which was an early pioneer in recovering streams from underground. The social and environmental benefits in Zurich are evident. Torrential rain in November forced many people across the country to leave their homes. The writer Edward Platt looks back at the effect of the record-breaking floods of 2013-14 and the toll it took on those caught up in the deluge. He talks to those responsible for trying to keep the water at bay, and asks what can be done to protect the vulnerable. The artist Tania Kovats’s work is preoccupied with our experience and understanding of water and the landscape. From collecting water from a hundred UK rivers to sculptural forms cast in wetsuits, and to the study of

Corporate rapacity and government collusion are at the centre of William Dalrymple’s history of the East India Company. He tells Amol Rajan how the company moved relentlessly from trade to conquest of India in the 18th century. But Dalrymple warns against the distortion of history both by those in Britain nostalgic for an imperial past, and Hindu nationalists in India.2019 marked the centenary of the Amritsar massacre in which more than a thousand Indians were killed by British soldiers. Although the events leading up to the atrocity are now well documented, Anita Anand has uncovered the extraordinary story of revenge which led to the shooting in London of the man responsible for the massacre. In August this year the Indian government revoked Kashmir’s special status, sparking protests in the Muslim-majority valley. But why has this region - once a princely state, until the end of British rule - become such a flashpoint for violence? Professor Sumantra Bose explores the consequence of the Indian government’s

Classicist Bettany Hughes has traced the history of the goddess known as Venus or Aphrodite. Originally depicted with a phallus on her head, Venus was later drawn and sculpted as a beautiful naked woman. Hughes tells Andrew Marr why this powerful deity of love was thought to corrupt and to inspire.Tenor Mark Padmore depicts the irrationality of desire in Benjamin Britten's Death in Venice. He plays the lead role in the Royal Opera House's new production, based on Thomas Mann's novella, in which a burnt-out writer succumbs to obsessive love. Britten wrote the main part for his partner, Peter Pears, with whom he lived through decades of homophobia.Unconscious desires and strange fantasies play out in the work of Dora Maar, one of the great Surrealist artists. Emma Lewis has curated an exhibition of Maar's photography and paintings, revealing an artist whose striking imagery rivalled that of her more famous lover, Picasso.Historian of philosophy Clare Carlisle discusses the Dutch philosopher Baruch Spinoza, one

Nothing is certain in this world except death and taxes. If this is true, then the comedian-cum-finance writer Dominic Frisby says it’s time we better understand the latter! He tells Tom Sutcliffe how taxes have shaped our past, are upsetting our present and could be the answer to changing our future. The economist Vicky Pryce also wants to change the future, by reforming capitalism so that it stops failing women. She interrogates the pay gap and glass ceiling. But she also argues that the free market is predicated on perpetuating inequality - and that it is women who bear the brunt.The free market economy was advanced during the Enlightenment. The academic Alexander Zevin explores how a century later economic liberalism became fused with political liberalism in Britain. And how the liberal message evolved through the pages of the Economist Magazine, founded in 1843. As BBC Radio 4’s Book at Bedtime prepares to read Voltaire’s satire Candide, Professor Judith Hawley looks back to the ideas that were fermentin