Start The Week

Edward St Aubyn is the award-winning author of the Patrick Melrose series. His new novel, Double Blind, also revolves around transformation and the headlong pursuit of knowledge. He tells Tom Sutcliffe that his characters range across the sciences – from genetics to ecology to psychoanalysis. And their investigations into inheritance, freedom and consciousness intertwine with their feelings of love, fear and greed.Isaac Newton is often revered as the scientific genius of the 18th century: an unworldly scholar who abandoned his intellectual life to rescue the country’s finances. But the academic Patricia Fara paints a more complicated picture in Life After Gravity. Here Newton is seen in the last 30 years of his life as he heads both the Royal Mint and the Royal Society – a scientist who revelled in the dirty worlds of money and politics. Chris van Tulleken is an infectious diseases doctor who has also forged a career presenting health and science programmes on radio and television. With his twin brother Xand

The journalist Matthew d’Ancona attacks the torpor and complacency which has come to dominate the political landscape. In Identity, Ignorance, Innovation he analyses what’s gone wrong in Britain from education and social care, to technological inequality. He tells Andrew Marr that far from demonising identity politics, the right needs to embrace a diversity of voices.But identity politics has become a major battleground in the culture wars in Britain and the US. The writer Kenan Malik has been charting its rise, and focuses his attention on the growing interest in ‘white identity’, and the debate around the so-called ‘left behind’ in traditional working class areas. The economist and Director of the LSE, Minouche Shafik argues that societal breakdown and increasing polarisation can only be healed with a new social contract fit for the 21st century. In What We Owe Each Other she draws on evidence from around the world to look at how we can re-evaluate the balance between the individual and society, between rig

400 years ago Robert Burton produced his labyrinthine masterpiece, The Anatomy of Melancholy – a work which was celebrated in the Renaissance for its understanding of the huge variety of causes, symptoms and cures of mental distress. In A User’s Guide To Melancholy the academic Mary Ann Lund looks back to this precursor of the self-help book. She tells Amol Rajan that we have much to learn from those who struggled with melancholy in the past.In Heavy Light, the writer Horatio Clare shares how his mind began to unwind; his growing mania followed by psychosis and his treatment in a psychiatric hospital. But he also details the journey of recovery and healing, and he investigates how society treats acute crises of mental health.The psychiatrist Ahmed Hankir understands only too well what it’s like to feel depressed and hopeless – he suffered from mental health difficulties during his studies. He has used his own experiences to produce The Wounded Healer which seeks to reduce stigma around mental health, blending

The deep sea is the last, vast wilderness on Earth. In The Brilliant Abyss the marine biologist Helen Scales dives below the surface to tell the story of our relationship with the ocean floor. With an average depth of 12,000 feet it remains a frontier for new discoveries and extraordinary creatures. But Helen Scales warns Andrew Marr of the unfolding environmental disasters as people seek to exploit this new world, far beyond the public gaze.The writer Philip Hoare explores nature through the work of the artist Albrecht Dürer. From his 15th century prints of the plague-ridden Apocalypse to his leviathans in the deep, Dürer’s works were a revelation. In Albert & the Whale Hoare writes about the enduring quality of his art and its powerful message about the fragile beauty of the natural world.The journalist Elizabeth Kolbert is the author of the international bestseller, The Sixth Extinction, which was a clear-eyed account of humanity’s impact on the Earth. In Under A White Sky she asks whether through scie

Kerri ní Dochartaigh was born in Derry-Londonderry at the height of the Troubles, to a Catholic mother and Protestant father. In Thin Places she traces a life affected by poverty, loss and violence, and the invisible border that runs through it. But she tells Kirsty Wark how the natural world has helped heal the traumas of childhood.For the writer Sally Bayley it was Shakespeare that brought her solace and ignited her imagination. Growing up in a working class household with no father figures Bayley roamed through his plays looking for companions and escape from her oppressive home. In No Boys Play Here: A Story of Shakespeare & My Family’s Missing Men she explores the crisis of male homelessness and mental illness.The award-winning actress Lisa Dwan has a deep affiliation with the works of Samuel Beckett. But in her latest performance she reaches back to the ancient Greek tragedians reimagined by another acclaimed Irish writer Colm Tóibín. In Pale Sister she recounts Sophocles’ tragedy of Antigone from t

What happens when real life collides with your digital existence – the writer and ‘Poet Laureate of Twitter’ Patricia Lockwood talks to Andrew Marr. In her highly original novel, No One is Talking About This, Lockwood’s narrator becomes overwhelmed as drama in the human world encroaches on the life she leads online.Roisin Kiberd is part of the internet generation and believes the line between online and IRL has become so porous as to become meaningless. From the lure of endless scrolling, to the glamour of self-optimisation and the boundless possibility of connectivity, Kiberd explores the ups and downs of this new reality in a series of essays, The Disconnect.In a new series on Radio 4, Sideways, Matthew Syed exploits different ways of seeing the world to connect disparate ideas and offer new insights. He examines the online craze of ‘randonauting’ – in which an app sends people on random adventures – to unpick the misunderstanding of probability using digital and real life examples. Producer: Katy Hickman

Britain is a direct product of its imperial past. So argues the writer Sathnam Sanghera in his latest book, Empireland. He tells Tom Sutcliffe how we need to move beyond simplistic feelings of shame or pride in Britain’s empire if we are to truly understand who we are.It’s not just the story of empire shaping modern Britain but the longer more entrenched history of class. In Snakes and Ladders: The Great British Social Mobility Myth, the historian Selina Todd explores how class distinctions still prevail today.Class and empire weave their way into the work of the poet Anthony Anaxagorou. His family is from Cyprus - an island deeply divided and with a history of colonisation. He charts his rise as a poet in the pocket-book series, ‘How to… Write it’. And his last collection, After the Formalities, explores the anxieties inherent in his British and Cypriot heritage. Producer: Katy Hickman

He was born into abject poverty in Czechoslovakia, fought for the British and was decorated for his heroism in WWII, and became a successful businessman and press baron courted by political leaders around the world. Yet Robert Maxwell ended his life reviled as the embodiment of greed and corruption. The writer John Preston discusses his book, Fall: The Mystery of Robert Maxwell, with Andrew Marr.The journalist Julia Langdon was appointed the political editor of the Daily Mirror in 1984 when Maxwell owned the newspaper. She looks back at his often extraordinary behaviour. But Langdon also examines the difficult and changing relationship between those in power in politics and the media moguls.Maxwell was brash and theatrical working from luxury apartments at his rechristened Maxwell House, complete with Doric columns at the entrance. Emily Bell, formerly a media journalist now academic at Columbia University, sees certain parallels with Trump Tower. But the media landscape since Maxwell’s days has changed drama

Mariana Mazzucato, Professor of Economics at University College London, tells Amol Rajan it’s time western governments took a braver approach to the biggest problems of our time – inequality, disease and environmental crisis. In her book, Mission Economy, she argues that capitalism has foundered. Taking inspiration from President Kennedy’s decision in 1962 to put a man on the moon by the end of the decade, she calls for a greater sense of purpose from governments and a bolder public-private cooperation. The former cabinet minister and Liberal Democrat leader Vince Cable looks back over the last 250 years to understand the power politicians have to transform their countries’ fortunes, for better or worse. In Money and Power – The World Leaders who Changed Economics he ranges from Thatcher to Trump, from Lenin to Bismarck to examine the interplay of economics and politics.But what happens when people begin to feel the economy is broken. In Why You Won’t Get Rich the journalist Robert Verkaik aims his ire at cap

Francis Bacon is one of Britain’s greatest twentieth century artists – a painter who captured and exposed the darker, stranger sides of life. He is the subject of a new biography, Revelations, by Annalyn Swan and Mark Stevens. Swan tells Andrew Marr how Bacon often fashioned his own autobiography, revelling in story-telling while immersed in the Soho nightlife.Francis Bacon never hid his homosexuality, even at a time when it was illegal in Britain. The celebrated script writer Russell T Davies is well-known for his depiction of the gay scene in Manchester with his 1990s series, Queer as Folk. He now turns his attention to what happened in the decades of the HIV/ AIDs crisis in the Channel 4 series, It’s A Sin.The composer Mark-Anthony Turnage took inspiration from a Francis Bacon’s triptych in his work Three Screaming Popes, combining expressionist complexity with English lyricism. 2020 was planned as a celebratory year for Turnage’s 60th birthday with several premieres scheduled. All were cancelled due to Co

The Acts of Union 1707 brought together England and Scotland, ‘United into One Kingdom by the Name of Great Britain’. But the historian Karin Bowie tells Andrew Marr that in the years preceding a growing number of pamphlets and demonstrations showed that many people were divided on the issue. In ‘Public Opinion in Early Modern Scotland c.1560–1707’ Bowie charts the growing debate across society. The failure of Scotland’s trading ambitions in the Darien Scheme also hit the country hard, both financially and emotionally.However the idea of an independent Scotland emerged surprisingly recently into public debate, according to academic Ben Jackson. In his book The Case for Scottish Independence he argues that an influential Scottish nationalism only began to take shape from the 1970s onwards. It was at heart a political project, born out of opposition to the Thatcher government. Ruth Wishart is a pro-independence journalist who has written about Scottish affairs for many decades. As s columnist for The Nationa

2020 has been disastrous for the arts in Britain and many people have lost their jobs as Covid-19 has swept through the country. Sir Nicholas Hytner has been working in the theatre for nearly four decades and he tells Andrew Marr about the unprecedented challenges that now face his industry. Hytner made his name and fortune in the 1990s with the musical Miss Saigon. Further successes came with theatre and film productions of The Madness of King George and The History Boys, and the sell-out One Man, Two Guvnors.He ran the National Theatre for twelve years before setting up his own commercial venture – with his business partner Nick Starr – the Bridge Theatre. During the year of the pandemic Hytner has sought to keep the theatre afloat with performances of Alan Bennett’s Talking Heads, and a specially adapted, socially distanced, but joyful, version of A Christmas Carol.Producer: Katy Hickman Photographer: Helen Maybanks

As the 850th anniversary of the murder of Thomas Becket approaches Andrew Marr explores the dynamic between church and state and what happens when the most powerful political friendships turn sour. The academic Laura Ashe explains the background to the murder in the cathedral on 29th December 1170. King Henry II had promoted the lowly born Thomas Becket to the highest positions in the land – first Lord Chancellor, then Archbishop of Canterbury. But their growing animosity and conflict over the rights and privileges of the church led to his infamous assassination by four of the King’s knights. In recent years the former librarian Christopher de Hamel has succeeded in identifying the Anglo-Saxon Psalter which Becket cherished in his lifetime and may even have been holding when he died. In The Book in the Cathedral: The Last Relic of Thomas Becket, de Hamel looks at what this book reveals about the life of Becket. He also compares the veneration for relics of the saints in the Middle Ages, with our relationship

Look into the night sky in the coming days and Jupiter and Saturn will appear closer than they’ve been since the early 17th century, according to the astronomer Stuart Clark. He tells Tom Sutcliffe it’s a beautiful great conjunction that happens once every 20 years, but this year is especially rare. In his book, Beneath the Night, Clark explores how the stars have shaped the history of humankind, inspiring awe and fascination throughout the centuries. It was the extremity and majesty of whales that inspired the writer Rebecca Giggs. In her latest book, Fathoms: the world in the whale, she fuses natural history, philosophy and science to look at our relationship with this most magnificent of mammals. She asks how far the lives of whales might shed light on the condition of our seas, and the impact of climate change.Artists have long taken inspiration for their work from the heavens and the natural world around them. In Shaping the World: Sculpture from Pre-History to Now, the world-renowned sculptor Antony Gor

Why do we laugh? This is the question the evolutionary ecologist Jonathan Silvertown sets out to answer in his latest book, The Comedy of Error. He looks back at laughter’s evolutionary origins, and to the similarities and differences in humour across cultures.The sell-out comic Sindhu Vee swapped a career in investment banking for one in comedy. She is an expert at exploiting cultural differences in her jokes, having been born in India, lived and studied in the Philippines and the US, before settling in the UK. John Mullan holds up Charles Dickens as a master novelist who could switch with ease from tragedy to comedy in a sentence. In The Artful Dickens he explores the tricks and ploys the writer used and how his humour has stood the test of time.Producer: Katy Hickman Photograph by Matt Crockett

Amol Rajan explores different ways of thinking, and how far humans can be seen as unique for their ability to invent. In The Pattern Seekers, Simon Baron-Cohen shows how humans have evolved remarkable ingenuity in every area of their lives – from the arts to the sciences – by using complex systemizing mechanisms. He says this ability to formulate if-and-then processes has driven progress for more than 70,000 years. He goes on to argue that the areas of the brain important for systemizing overlap with those for autism. As the Director of the Autism Research Centre at Cambridge University, Baron-Cohen wants to challenge people to think differently about an often misunderstood condition. The archaeologist Rebecca Wragg Skyes is also seeking to challenge people’s perceptions. In Kindred: Neanderthal Life, Love, Death and Art, she builds a picture of an ancient ancestor who was far from being a brutish thug. She depicts the Neanderthals as curious and clever connoisseurs of their world: technologically inventive

‘A text is not a text unless it hides from the first comer, from the first glance, the law of its composition and the rules of its game. A text remains, moreover, forever imperceptible’. So wrote the superstar philosopher Jacques Derrida. But what does it mean to question and deconstruct everything we think we know? In a new biography of Derrida titled An Event, Perhaps, Peter Salmon explores the life and works of one of the most enigmatic of thinkers. He questions how far Derrida’s ideas have led to today’s ‘post-truth’ age? Virginia Woolf's essay ‘How Should One Read a Book?’ posed the question: ‘‘Where are we to begin? How are we to bring order into this multitudinous chaos and so get the deepest and widest pleasure from what we read?’ The English professor Alexandra Harris looks at whether Woolf’s answer stands the test of time.Bernhard Schlink’s literary career took off in 1995 with the publication of his novel The Reader, which became an international bestseller. His latest work, Olga (translated into

Ireland itself is a main character in Kevin Barry's new short story collection, That Old Country Music. He brings the western regions to life in stories set firmly in Ireland's present day but with an ancient, magical past lingering in the background. A pregnant teenager waits for her robber boyfriend, a factory worker falls for a Polish waitress, and a police officer seeks a known criminal, in stories set amidst wild and flourishing countryside.The concrete walls and tower blocks of Peckham in south London are not often the subject of poetry. For his debut collection, Poor, Caleb Femi pays tribute to the streets that shaped him as a child. He brings to life the schoolboys, rappers, artists, pastors and gentrifying neighbours of Peckham, an area where it is possible to walk two and a half miles through an estate of 1,444 homes without a single step on the ground.Daisy Johnson became the youngest ever Booker Prize nominee with her debut novel, Everything Under, and quickly established herself as a master of cr

Sir Roger Penrose was jointly awarded the Nobel Prize in physics this year for his ground-breaking work on black holes and their relationship with the general theory of relativity. He looks back at his extraordinary career with Andrew Marr – from his early interest in mathematical patterns and the ‘impossible’ works of Escher, to his revolutionary use of mathematics in cosmology and his continued fascination with the beginning and end of time. Carlo Rovelli is a theoretical physicist who researches quantum gravity, as well as a best-selling author. In his latest collection of essays, There are Places in the World Where Rules are Less Important than Kindness, he demonstrates a curiosity that crosses the boundaries from the sciences to the arts. He reflects on everything from Newton’s alchemy to Einstein’s mistakes, and from Dante’s cosmology to Nabokov's butterflies. The world underwater is the physicist Helen Czerski’s playground. The focus of much of her research has been the physics of breaking waves and bu

The Latin scholar Shadi Bartsch has written a new translation of Virgil’s The Aeneid. She tells Kirsty Wark how this timeless epic about the legendary ancestor of a Roman emperor has been constantly invoked and reinterpreted over its two thousand year history. She argues that this poem still has much to say to contemporary readers about gender, politics, religion, morality, nationalism and love.It was while arguing about the merits of the Aeneid’s tragic queen, Dido of Carthage, that the classicist Natalie Haynes decided it was time to rescue the women in ancient myths. Centuries of male interpretations, she argues, has led to the demonization and dismissal of the likes of Medusa, Phaedra and Medea. In Pandora’s Jar: Women in Greek Myths she goes back to the original stories, reinstating the more complex roles given to these women in antiquity.In the 17th-century the Italian painter Artemisia Gentileschi drew inspiration from the women in ancient myths, allegories and the Bible, as seen in a new exhibition of