Psychedelics Today

In this episode, Joe interviews Deborah C. Mash, Ph.D.: neuroscientist; Professor Emerita of Neurology and Molecular and Cellular Pharmacology at the University of Miami Miller School of Medicine; and leading researcher in addiction and brain disorders for over 30 years. She is also the CEO and Founder of DemeRx Inc., a clinical stage drug development company working to advance ibogaine and its active metabolite, noribogaine, for the treatment of opioid use disorder. She talks about the Federal and state complications behind ibogaine research, the need for partnerships between clinics and researchers, what needs to be done to collect much needed Phase II and III ibogaine data, and why this all has to be in partnership with the FDA.  And she discusses much more: her story of how studying Cocaethylene led to her finding out about ibogaine; ibogaine and QTc-prolongation; deaths related to iboga and the amount of variables that aren’t considered; how the French were essentially using noribogaine in the 1930s; and

In this episode, David interviews Madison Margolin: NY-based, psychedelics and Judaism-focused journalist; host of the Set & Setting podcast; co-founder of DoubleBlind Magazine and the Jewish Psychedelic Summit; and author of the soon-to-be released, Exile & Ecstasy: Growing Up With Ram Dass and Coming of Age in the Jewish Psychedelic Underground. They explore the relationship between Judaism and psychedelics, with Margolin sharing her experiences growing up in a Hindu-Jewish family; her personal journey with her Jewish identity; and how her use of psychedelics has deepened her life. She talks about the significance of Jewish holidays, and how holiday traditions connect them to nature and themselves in a very psychedelic way; the importance of intentionality; the beauty in dancing through an uncomfortable ayahuasca experience; the Jewish Psychedelic Summit; whether or not ancestors were using substances (and does that matter?), and why being in Israel feels so different – and psychedelic.  Margolin is

In this episode – with the ​2024 edition of Vital​ announced and applications officially open – we’re launching another series of Vital Psychedelic Conversations, with David hosting Jasmine Virdi: Vital instructor, writer, educator, and activist who works at Synergetic Press and volunteers for Fireside Project; and Tabata Gerk: Vital student, psychotherapist, and facilitator. As always, they discuss what they think the most vital conversation should be right now, largely expressing concerns over the medicalization of psychedelics and the idea of a ‘traumadelic culture,’ where psychedelics are often only seen as healers of trauma and not doorways to mysticism and new ideas. And they point out another concern: the romanization of Indigenous culture and not recognizing that these are contemporary cultures that are affected by the same Western, capitalist paradigms that affect us all. They also discuss the concept of epistemic injustice and needing to respect other ways of knowing; hyper-individualism and why we

In this episode, Joe interviews Ethan Nadelmann: author, speaker, Founder and former Executive Director of Drug Policy Alliance, host of the PSYCHOACTIVE podcast, and one of the leading voices in drug policy reform and harm reduction.  Nadelmann shares his journey from Princeton University to founding Drug Policy Alliance, to working with George Soros, encouraging Gary Johnson to push cannabis legalization, and interacting with prominent figures like Milton Friedman and Grover Norquist. He explores the motivations behind the drug war, the massive growth of incarcerations it led to, why the US spread its war on drugs abroad even when it went against our best interests, and, thankfully, the progress made in fighting the drug war – particularly with cannabis and psychedelics. And he discusses much more: the banning of drug testing kits; the damages of our slow learning curve against the idea of a safe supply; the risks of under-prescribing opioids for people who actually need them; how libertarians, the right, a

In this special episode, Melanie Pincus, Ph.D. and Manesh Girn, Ph.D., who joined David in episode 403 to discuss the launch of their new course, essentially interview each other. As the 2nd edition of their popular course, Psychedelic Neuroscience Demystified, begins on November 1, we wanted to give them a chance to highlight some of the aspects of neuroscience students can expect to learn in the course, and what so many people who are interested in psychedelics don’t fully understand: What does neuroplasticity actually entail? Can one predict if a patient is more apt to have an experience with ego dissolution? How does the amygdala relate to mood disorders? When are critical periods of greater plasticity and socialization at their most beneficial? How does neuroplasticity relate to chronic stress? They also discuss lessons they’ve received from their own journeys; why they created the course; serotonin; psychological flexibility; body-based versions of self vs. memory-based versions; psychedelics and re-enc

In this episode, Kyle interviews Rachel Harris, Ph.D.: Psychologist in private practice for over 40 years, researcher who has published more than 40 peer-reviewed studies, and author of the new book, Swimming in the Sacred: Wisdom from the Psychedelic Underground. She talks about graduating college and going straight to Esalen, where she had little concern over therapy or integration, and how, after 20 years of ayahuasca experiences, she learned to see psychedelic-assisted therapy and ceremonial, transformational experiences as very different things. She discusses her ayahuasca journeys; a surprising MDMA experience; what having an ongoing relationship with the spirit of ayahuasca means; Ann Shulgin’s concerns over going through death’s door while in a journey; what true integration is; how psychedelics can help prepare for death, and more. And she talks about her new book, Swimming in the Sacred, which collects the stories, unique perspectives, and wisdom of 15 female elders who have been working in the unde

Last year, Joe attended his first Burning Man, and sadly, we didn’t hear much about it. In this episode, recorded just a few days after Joe returned from his second outing of nearly 12 days on the playa, Victoria changes that, asking Joe all the burning questions we all want to know. He talks about preparing for Burning Man and the numerous obstacles he and his partner, Ali, encountered on their very slow journey there; the media’s interpretation of the rain and mud vs. the reality of being there in the middle of it all; the bogus reports of an ebola outbreak and disaster zone surrounded by FEMA officials (and was that all a prank by Burners?); the debate over the environmental impact of such a massive event, and more. And he talks about the many joys of Burning Man: how, despite the weather and needing to remain at camp more, the community, abundance, embracing of all that is weird, and passion to share and make the best of it all made this a better year for him in many ways. He learned the importance of pat

In this episode, Kyle interviews General Stephen Xenakis, MD: an adult, child, and adolescent psychiatrist who retired from the U.S. Army in 1998 at the rank of Brigadier General and began a career starting up medical technology companies and clinical practice to support human rights and new methodologies of healthcare.  In June, he became the new Executive Director of the American Psychedelic Practitioners Association (APPA), whose mission is to bring practitioners together as a community; develop the best training programs and practices; shift to a more patient-centered, integrated model of care; eventually accredit practitioners to practice with legal substances; and overall, help to make these new modalities more mainstream.  He discusses their path to success, which began with their publishing of the first professional practice guidelines for psychedelic-assisted therapy practitioners, and will continue on with ethical guidelines and clinical practice guidelines in the future. And he talks about the idea

In this episode, David interviews Dr. JoQueta Handy, Ph.D., IMD: speaker, author, educator, Natural Integrative Health Practitioner, and CEO and Chief Visionary of Brilliant Learning, Handy Wellness Center, and Brilliant Blends. She shares childhood memories of growing up on her Grandparents’ farm, where she developed a deep appreciation for nature, staring at the stars, and the beauty in stillness, and how coming back to that stillness has been key in her life and psychedelic journeys. The conversation then shifts to all that she’s learned through her work with children on the autism spectrum: the problems of putting people into boxes; how autism affects everyone; the different ways people learn; the connection between autism and the gut microbiome; and how she has learned more from some of these children than any book could teach her – culminating in a story of discovering that a very challenged child people were ready to give up on could actually read and comprehend everything he was hearing. She discusses

In the first-ever episode of Hyphae Leaks, Mary and Reggie sit down with Joe Moore and share their backgrounds, impetus for launching a psychedelic tell-all podcast, and what listeners can expect from the first season. Want to dig in on some of the topics discussed today? Quick links: Quick stats on biodiversity and Indigenous communities. Excellent reporting on why Indigenous lands protect biodiversity. Why we can’t blame the unhoused issue on drug decriminalization. Follow Reggie Harris on Instagram Follow Mary Carreón on Instagram Follow Hyphae Leaks on Instagram Subscribe to the Hyphae Leaks Substack. Catch Season 1 of Hyphae Leaks streaming NOW wherever you get your podcasts. New episodes every third Wednesday until Dec. 20. Rate, review, and subscribe!

In this episode, David interviews the President of the Psychedelic Medicine Association, host of the Psychedelic Medicine Podcast, and Psychedelics Today advisory board member and Vital contributor: Lynn Marie Morski, MD, JD. She shares her journey with psychedelics and how they enabled her to leave a toxic job and pursue her passion for advocacy with vitality, and how important it is to focus your energy where it's best used. She talks about where we find ourselves in the psychedelic space based on Psychedelic Science 2023, as well as her recent TV appearances and the responsibility of preaching to the non-choir. And she discusses the idea of perfectionism in today's age; the need for psychedelic people to be involved in non-psychedelic conferences; the complications behind requiring physicians to experience psychedelics; the concept of it being malpractice for a physician to not mention psychedelic options; and the Psychedelic Medicine Association's upcoming virtual conference: Sana Symposium 2023, which ha

In this episode, Alexa interviews Chase Hudson: Founder of HempLucid, a premium CBD wellness brand. Hudson discusses his journey from being a firefighter to becoming involved in the cannabis and hemp industry, the origins of HempLucid, the restrictions they faced, and their current genetics and flagship water soluble tincture. He talks about the benefits of CBD and cannabis used in conjunction with psychedelic therapy - especially ketamine-assisted therapy, which he gives to his employees as a benefit. And he talks about Lamar Odom and the documentary he executive produced, "Lamar Odom Reborn," which chronicles how Odom came back from rock bottom through high dose CBD, iboga, and ketamine therapy. He also discusses the idea of cannabis as a gateway drug to healing; the need for insurance to cover psychedelic therapy; the changing landscape of Utah from religious ideology to psychedelics; ketamine as the bridge between old and new models of healthcare, and more. And they talk about their own journeys a lot, wi

In this episode, David interviews East Forest: Portland, OR-based producer, podcaster, ceremony guide, and musician, specializing in ambient, electronic, contemporary classical, and indie pop music largely to guide listeners through deep journeys.   Forest discusses his live performances and influences; how his music pairs with journeys and specific psychedelics; the difference in the connection and vibe from a live performance vs. a recording; the difference between single-artist music created specifically for sessions vs. Spotify playlists; the inhumanity of generative music; his Journey Space online music and journey platform; and the challenges of making money in a time when music is more prevalent than ever, but also more in-the-background and diluted.  He talks a lot about sound itself: the role of rhythm and sound in communication and personal transformation; how richer overtones and increased layers of sound increase effects; research into very low pulsating tones, and how more synthesized sound and t

In this episode, Joe interviews Satya Thallam: Policy Advisor at the international law firm, Arnold & Porter; and longtime policy expert based in Washington, D.C. who previously served in senior roles at both the White House and the U.S. Senate. Thallam was the lead author and negotiator of the Federal Right to Try Act, which grants terminally ill patients access to experimental therapies and substances that have completed Phase I testing but have not yet been approved by the FDA. He discusses its intricacies and benefits, how psychedelics were not a focus but were always obvious, whether or not it allows people to grow their own mushrooms, and more. He talks abut the implementation of the first Federal legalization of hemp under the Farm Bill in 2018, breaking down the history and detail of how it came to be, and why a difference of .3% in weight truly matters when establishing law. He discusses the changing landscape of politicians and psychedelics; how local action creates a culture of inspiring Washin

In this episode, Kyle interviews Lisa Wessing: Clinical Psychologist and facilitator specializing in harm reduction at Kiyumí retreats in The Netherlands.  Wessing shares her personal journey and the shift from being uninspired with studying psychology to being a part of space-holding in Mexico and finding her true path. She dives into the world of Kiyumí retreats, discussing their holistic healing approach using psilocybin, somatic movement, dance expression, and other methods supporting their four pillars of embodiment, nature, mindfulness, and art. She discusses their more long-term program with Dr. Gabor Maté integrating his Compassionate Inquiry framework; their Equity Program, which offers partial or full funding for people who may not have the financial resources or who come from marginalized communities (e.g. BIPOC & Queer); and the importance of integration as a continuous process and checking in with people much later to build their “Kiyumíty.” Much of this discussion covers the challenges of so

In this episode, recorded in-person at Psychedelic Science 2023, Kyle interviews Senator for the Mexican Green Party, Alejandra Lagunes. Lagunes is the first Senator in Mexico to promote the use of psychedelics, and has been organizing open parliaments to foster collaboration between researchers, scientists, politicians, and Indigenous people, culminating in a groundbreaking decriminalization initiative to decriminalize psilocybin and psilocin from list 1 to list 3 (meaning they could be prescribed), create a new chapter for entheogens (and move mushrooms there), build an economically beneficial framework for Indigenous people, protect ancestor knowledge by law, and make big bioconservation moves with changes to environmental laws.  She discusses her personal journey with depression, anxiety, and a life-saving ayahuasca journey; how Covid uncovered a crisis in meaning and an openness to talk about mental health; the need for accessibility and safety in psychedelics against challenges in politics and policy im

In this episode, Joe interviews Stéphane Lasme, a former professional basketball player from Gabon who is now a partner at SteddeCapital, a private markets investment platform investing long-term capital into U.S.- and Africa-based opportunities across sports ownership, infrastructure, technology and plant medicine. Lasme speaks of his childhood, growing up in Gabon with more traditional Catholic values while journeying deep into the jungle to visit his Grandmother every summer. It was there that he embraced the cultural aspect of Gabon and community, and first learned of iboga, which he had a profound experience with at age 12, and would later revisit in his basketball days. He discusses the drive and passion that led him to become the first person from Gabon to play in the NBA, and the subsequent pressure, stress, cultural differences, and “ok, what now?” moments that came at the end. He talks about Gabonese traditions; how iboga improved his stress relief and mental focus; how embracing yoga and Buddhist m

In this episode, Kyle interviews The Susan Hill Ward Endowed Professor of Psychedelics and Consciousness Research at Johns Hopkins, and renowned researcher of nearly 20 years: Matthew W. Johnson, Ph.D. Recorded in-person at MAPS’ Psychedelic Science after running an 8-hour workshop on psychedelic therapy for addiction treatment, Johnson was still happy to sit down with PT to explore a wide range of topics: the under-researched concept of integration; how to best take advantage of optimal neuroplastic windows; why psycholytic therapy used to be more common; how our current protocols and research models are largely arbitrary; and his hopes for new, experimental, and flexible models of psychedelic therapy. He also discusses his ongoing smoking cessation studies; the Oregon model (are we doing therapy or not?); misrepresentation in psychedelic therapy and knowing your lane; and the role of music in psychedelics: why shouldn’t people pick the music they know will give them goosebumps? Click here to head to the sh

In this episode, Joe interviews Maya Albert: Co-Founder of the Psyched conference, and Director of Operations at Tabula Rasa Ventures and the Synthesis Institute. She shares her journey of how she became involved in the psychedelic space through her mother, and her personal experience as a patient in a clinical trial on psilocybin for the treatment of anorexia – a much more common and deadly affliction than most people realize. She discusses her involvement with the various psychedelic gatherings surrounding Davos and the World Economic Forum, as well as the work she’s doing with Tabula Rasa and some of their clients seeking to expand insurance coverage to psychedelic-assisted therapy.  She discusses the Synthesis Institute’s recent struggles that shook up the psychedelic space, what they’re doing to save the company, how Retreat Guru has helped them, and the implications for the wider psychedelic movement. And she talks about much more: the legality and vetting process for training in Oregon and Colorado; tr

In this episode, Kyle interviews the Founder and CEO of FreshCap Mushrooms and host of The Mushroom Show on YouTube, Tony Shields. He talks about how an early interest in lucid dreaming sent him down a psychedelic path, and how, as his interest in mushrooms has grown, he’s watched the culture shift from a narrative of mycophobia to one of appreciation and interest. With FreshCap Mushrooms and The Mushroom Show, he aims to provide much needed education around this vast and mysterious world of fungi. He talks about the thriving psilocybin scene in Jamaica, and how, through filming a documentary there, he learned how much communities still don’t know about mushrooms, how much tourism supports the country, and how much of a special vibe Jamaica has for psilocybin retreats. And he discusses much more: why lion’s mane should help with concussions and TBIs; indications mushrooms could heal, from long Covid to paralysis; concerns over over-medicalization; why Terence McKennas’ ideas weren’t as crazy as many thought;